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COVEX S.A.



Cooperation history

Covex S.A. is a Spanish chemical and pharmaceutical company which is primarily engaged in the business of the production and commercialization of API (active pharmaceutical ingredient(s)) raw materials, pharmaceutical products and dietary supplements, especially made of Vinca alkaloids. We commenced business relationship with Covex in 2009 and were granted the exclusive right to market, promote and sell its Vinpocetine API products in China.

To further enhance our business cooperation with Covex, with a view to maintaining our established relationship and improving our Company’s prospects for renewing or extending our exclusive right granted by Covex, We entered into a unit purchase agreement with Covex in 2012 and held approximately 24% equity interest in Covex. In order to enhance our direct influence over Covex, We entered into the share acquisition and debt acquisition agreement with Covex on 1 July 2014. We will acquire approximately 44.6% of the equity interest in Covex and will acquire most debts of Covex. Following completion of the share acquisition, We will hold approximately 68.6% of the equity interest in Covex. Covex will become a subsidiary of us and will be consolidated into the financial statements of us.


About Covex S.A.

Covex S.A. is a European chemical and pharmaceutical company, manufacturer of API raw materials, pharmaceutical products and dietary supplements.

Today Covex is the largest manufacturer of Vinca alkaloids (Vinpocetine, Vincamine, Vinburnine and Vincagenol®), for enhancing memory and other cognitive functions, with competitive prices worldwide.

Covex has been supplying its compositions principally to the pharmaceutical industry for years. Our activity is currently expanding towards the dietary supplements and energy drinks sector.

Covex has developed a unique way of extracting products in advanced chemistry meaning that, today, it can guarantee high quality production at optimum standards able to compete internationally.

As a result of its intensive investment in R&D, Covex owns more than 100 patents in over 100 countries. Covex is leader in the production of the periwinkle family products.

Customer care at its best

Outstanding quality products

Vincamine alkaloids products

European factory, GMP-certified

Xcellence in service, quality and price


Products:

Vinpocetine

Vinpocetine is a derivative of Vincamine, naturally occurring in Crioceras longiflorus. Clinical studies suggest that it facilitates cerebral metabolism by improving cerebral blood flow, increasing glucose and oxygen utilization by neurons and concentration of neurotransmitters involved in the process of memory formation.

Clinical studies have also shown that Vinpocetine may help to maintain healthy microcirculation in the inner vital organs of ears and eyes. Research has shown that the effects of this compound go beyond mere prevention and turn it into a Powerful Memory Enhancer.

Vincamine

Vincamine is a purified extract of Vinca minor L. (Periwinkle plant). Used as a cerebral vasodilator for enhancing mental alertness, it increases blood flow to the brain and improves its oxygenation.

The original use of this plant goes back to European traditional home remedy with a series of various applications. This herb is well known and widely used in popular medicine as an important component of herbal teas against nervousness in the elderly suffering from insomnia, anxiety and aggressiveness.

Vinburnine

Vinburnine, a natural occurring product found in the plant Hunteria eburnea P., obtained by semi-synthesis from Vincamine, is a muscle oxygenator. Clinical trials show the effects of Vinburnine especially in oxygen release from red blood cells.

Covex obtains Vinburnine through semi-synthetic process and distributes it worldwide as a high quality bulk raw material. Its main application as a dietary supplement is to boost the metabolism of glucose inside the muscle. Every training athlete or person doing fitness exercises can obtain maximum muscle performance by taking vinburnine as a catalyst of physical work.

Vincagenol®

It is a standardized and enriched Vinca minor l. extract containing indole alkaloids. The main indications for Vicagenol® are directly related to its properties as a vasodilator and its effects.

By increasing blood flow in the brain, it is beneficial in improving physical and neurological disorders such as memory loss, lack of concentration and attention, dementia, tinnitus, visual disturbances and depression, among others.

The extract improves metabolism and utilization of oxygen by red blood cells, which allows athletes and people whose work requires great physical or psychological stress, to increase their endurance and achieve the desired results.

Vincagenol® is a perfect candidate for the preparation of (nutritional or dietary) supplements.

Vinponature®

Vinponature® is a very high quality natural form of Vinpocetine specially designed for use in nutraceuticals, dietary supplements and functional foods for memory enhancement.

Vinpocetine is a very well known ingredient in Europe where it has been sold as a drug for the last 30 years. Vinpocetine is well known among neurologists, and widely distributed worldwide.

Vinpocetine was categorized as a dietary supplement by the DSHEA law in July, 1999. Since then, Covex has been supplying to many manufacturers in the U.S. market, VinpoNature® (Vinpocetine) to formulate dietary supplements for the improvement of memory, concentration, mental alertness, focus, attention.

Oxopocetine®

Oxopocetine® is water soluble form of Vinpocetine (citrate), allowing a rapid absorption and accordingly a better bioavailability of the same pharmacological action increasing and showing less toxicity than Vinpocetine (API).

The results of scientific studies show that vinpocetine citrate produces an effective increase in the cerebral circulation, is useful in cases of cerebrovascular disease and neurological treatments related to brain oxygenation, especially in people of advanced age.

Oxopocetine® in combination with caffeine (coffee, cocoa, tea and cola), can produce a synergistic increase in memory. It is specially designed for use in functional beverages and dietary supplements.

Vinpocetine Covex 5mg

Vinpocetine 5 mg improves cerebral blood flow, decreases cerebral vascular resistance and increases cerebral oxygen and glucose utilization. Vinpocetine 5 mg inhibits phosphodiesterase activity, prevents platelet aggregation and adenosine intake by erythrocytes.

It diminishes or suppresses disturbances due to hypoxia or deficient cerebral metabolism. Vinpocetine Covex 5mg is marketed as a prescription product in Azerbaijan, Armenia, Belarus, Bulgaria, Cuba, Georgia, Hungary, Kazakhstan, Latvia, Lithuania, Moldova, Mongolia, Portugal, Czech Republic, Slovakia, Spain, Russia, Ukraine.


Contact Covex:

Factory

Acero 25

28770 Colmenar Viejo, Madrid

Spain

Tel.: (34) 91 845 02 00

Commercial Office

Ronda de Valdecarrizo 41C, 1º

28760 Tres Cantos, Madrid

Spain

Tel.: (+34) 91 804 45 45

Email: info@covex.com

Web: www.covex.com